k ka Elimination rate constant Absorption rate constant λz Terminal rate constant MAT MRT Mean absorption time Mean residence time PK PopPK Pharmacokinetics Population pharmacokinetics Q …

Population PK analysis investigate and identify fixed effect sources of variability (covariates) which influence the PK and PD of a drug.

(Preferred) Using Bayesian software programs, embedded with a PK model based on richly sampled vancomycin data as the Bayesian prior, to optimize the delivery of vancomycin based on the …

PK data collection for an active drug compound is performed routinely in all clinical trials since it is a critical part of measuring the safety and efficacy of an experimental treatment and in determining the …

Conventionally, AUCs are assumed to be log-normal distributed. See the help file auc.complete for some corresponding ex-amples. An object of the class PK containing the following components: est …

The final guidance entitled "Population Pharmacokinetics" describes the application of population PK in drug development and its role in informing therapeutic individualization.

Now you see the relationship between pH and pK. The pH actually is derived from the properties of dissociation of the weak acid/base and the concentration of the acid (HA) and its conjugate base (A-).